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While this effect wanes with time, Semaglutide GLP-1 primarily helps treat obesity by acting on the brain

Because the medication intentionally slows gastric emptying, some patients may experience nausea, fullness, or bloating, symptoms similar to gastroparesis

7 Still, Le, who is also a general surgery registrar at Royal Melbourne Hospital, says, I think it is too early to say this is a robust, durable, and generalizable effect given the high heterogeneity of underlying studies. He notes a need for more rigorous randomized controlled trials with longer follow-up times to better characterize the impact of these medications on weight and OSA together, as well as gain a better understanding of effect size, optimal doses, side effects, interactions with other medications, and impacts on other comorbidities

For individuals managing chronic back pain, it is critical to weigh these potential risks with the benefits of the medication

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